Fertility Treatment IUI Treatment

Intrauterine insemination in a less invasive fertility treatment to support conception and family building.

IUI Treatment

If you have been trying to conceive without success, intrauterine insemination (IUI) may be one of the fertility treatment options available to you. IUI is a relatively simple and less invasive form of assisted reproduction that can help improve the chances of sperm reaching and fertilising an egg.

What is IUI?

IUI, or intrauterine insemination, is a fertility treatment where specially prepared sperm are placed directly into the uterus of the partner carrying the pregnancy around the time of ovulation. This shortens the distance sperm need to travel to reach the egg and may improve the chance of fertilisation and pregnancy.

IUI can be performed using sperm from a male partner or donor sperm, depending on your circumstances.

Compared with IVF, IUI is less invasive, less costly, does not involve egg collection, and is often considered earlier in the treatment journey for selected patients.

IUI may be recommended for:

Solo women using donor sperm and same-sex female couples may also be able to grow their families through IUI.

For some people, IUI may be recommended before considering IVF, while others may be advised that IVF or another fertility treatment is more appropriate based on age, fertility history, or underlying conditions. Dr Anna will discuss whether IUI is an appropriate treatment option for your individual situation.

The IUI process

As a more natural approach to assisted reproduction, IUI is a less involved process compared to IVF or ICSI but still requires a few key steps and precise timing.

1

Fertility assessment and cycle planning

Before treatment begins, Dr Anna will review your medical history, results of fertility investigations, and any previous treatment. The partner carrying the pregnancy may need additional testing to assess ovulation and condition of the fallopian tubes, while the partner providing the sperm may benefit from semen analysis to understand if IUI is a suitable treatment option. 

The timing of IUI is very important, so understanding your ovulation pattern is an essential part of treatment planning.

2

Ovulation tracking

IUI is carefully timed to coincide with ovulation, when an egg is released from the ovary. Ovulation may be monitored using blood tests, ultrasound scans, or ovulation predictor kits.

Some women undergo IUI during a natural menstrual cycle, while others may use medication to stimulate ovulation and improve the chance of releasing an egg at a predictable time.

3

Sperm preparation

On the day of the procedure, the sperm sample is prepared in a laboratory. If you are conceiving with donor sperm, this involves thawing the sperm sample. If a male partner is providing the sperm, he can produce the sample in a private suite on-site. The preparation process separates healthy, motile sperm from seminal fluid and debris, helping improve the quality of sperm used during insemination.

4

The insemination procedure

During the insemination step, the prepared sperm sample is placed directly into the uterus of the female partner using a long, thin tube known as a catheter. The procedure is usually quick and performed in the clinic without anaesthetic.

Most people describe insemination as involving mild discomfort at most, similar to a cervical screening test. You can generally return to normal daily activities shortly afterwards.

5

Pregnancy testing

A pregnancy blood test is usually performed around two weeks after the procedure to determine whether conception has occurred.

Understanding IUI success rates

IUI success rates vary depending on several factors, including age, ovulation, sperm quality, underlying fertility conditions, and whether fertility medications are used.

In general, IUI tends to be more successful in younger women and in cases where there are no significant issues affecting egg quality, sperm health, or fallopian tube function.

Though the IUI success rates per cycle are lower than IVF, some people may still choose to try IUI first as they prefer a less invasive and more natural approach. In other situations, Dr Anna may recommend starting with IVF if IUI is unlikely to provide the best chance of success.

During your consultation, Dr Anna will discuss your individual likelihood of success and help you understand the benefits and limitations of IUI based on your specific circumstances.

Frequently Asked Questions

There are no specific guidelines about when to keep persisting with IUI versus moving on to IVF, but most people will go through around three IUI cycles before considering other options. This is a personal decision and can be influenced by factors such as your financial situation, emotional capacity to keep trying, and age.

IUI involves placing prepared sperm directly into the uterus around ovulation to support natural fertilisation inside the body. IVF involves collecting eggs and fertilising them with sperm in a laboratory before transferring the resulting embryo into the uterus. IVF is generally more complex and invasive but may offer higher success rates in some situations.

No, PGT is not available with IUI. PGT requires sampling cells from the developing embryo, which can only be accessed when this embryo is grown in the lab. If having preimplantation genetic testing is important to you for your peace of mind or based on your genetic history, IVF or ICSI may be a more suitable treatment.